| February 20 | Swiss and German mercenaries desert Francois I's army |
| February 24 | Battle at Pavia: Emperor Karel V's troops beat French king |
| February 24 | Imperial forces defeat French in battle of Pavia |
| March 20 | Paris' parliament begins pursuit of Protestants |
| May 10 | Church reformer John Pistorius caught in the Hague |
| May 12 | Battle at Boblingen: Zwabische Union beats rebel Wurttembergse farmers |
| May 15 | German boer army surrounded/slaughters 5,000; ends Boer war |
| May 17 | Battle at Zabern: duke of Lutherans beats rebels |
| June 9 | Tax revolt in Hertogenbosch |
| July 11 | Trial against "heretic" John Pistorius at The Hague |
| July 19 | Catholic German monarchy form Union of Dessau |
| September 7 | Trial against "heretic" John Pistorius ends in the Hague |
