| January 30 | Adrian van Goes becomes land advocate of Holland |
| April 14 | Battle at Carignano: French troops under Earl d'Enghien beat Swiss |
| May 1 | Turkish troops occupy Hungary |
| May 17 | Scottish earl Matthew van Lennox signs secret treaty with Henry VIII |
| May 23 | German emperor Charles V recognizes king Christian III of Denmark |
| July 14 | English troops attack The Canal |
| August 17 | Imperial/English armies occupy Saint-Dizier France |
| September 14 | Charles and Francois I sign Peace of Crepy |
| September 18 | Charles V of Germany and Francis I of France sign Peace of Crepy |
| September 18 | English King Henry VIII's troops occupy Boulogne |
| September 18 | Peace of Crepy: German emperor Charles V and French king Francois I |
| September 30 | King Henry VIII draws his armies out of France |
| November 10 | Antwerps painter John Matsys banished |
| November 19 | Pope Paul III opens council of Trente |
