| January 10 | 1st sitting of "Vurige Chamber" in Paris |
| February 2 | English Edward Seymour duke of Somerset, freed |
| February 7 | Giovanni Maria del Monte elected Pope Julius III |
| March 24 | France and England sign Peace of Boulogne |
| April 2 | Jews are expelled from Genoa Italy |
| April 28 | Powers of Dutch inquisition extends |
| April 29 | Emperor Charles V gives inquisiters additional authority |
| July 7 | Chocolate introduced |
| September 5 | William Cecil appoints himself English minister of foreign affairs |
| November 14 | Pope Julius III proclaims new seat on Council of Trente |