| January 7 | Boris Godunov seizes Russian throne on death of Feodore I |
| January 8 | Genoa Italy expels Jews |
| January 8 | Jews are expelled from Genoa Italy |
| January 12 | Pope Clement VIII seizes duchy of Ferrara on death of Alfonso |
| February 17 | Boris Godunov chosen tsar of Russia |
| February 21 | Boris Godunov crowned tsar |
| March 11 | Countess Charlotte of Nassau marries duke Claude de la Tremoille |
| March 20 | French king Henri IV and duke van Mercour sign treaty |
| March 25 | Cornelis de Houtman's fleet departs for East-Indies |
| April 13 | Edict of Nantes grants political rights to French Huguenots |
| April 30 | 1st theater performance in America (Spanish comedy-Rio Grande) |
| May 1 | Jacob van Necks merchant fleet departs for Java |
| May 2 | France and Spain signs Peace of Vervins |
| May 6 | Arch duke Albrecht and Isabella become monarch of Southern Netherlands |
| June 30 | King Philip II moves to Escorial palace |
| July 10 | Spanish theater plays "Moros y Los Cristianos" in Rio Grande |
| August 4 | London's head office of Hanze closed |
| August 21 | Deed of Transfers proclaims Netherlands independence |
| September 1 | Spanish king Philip II receives sacraments |
| September 17 | Netherland sailors discover Mauritius |
| October 15 | Spanish general strategist Bernardino de Mendoza occupies fort Rhine |
| November 8 | Spanish troops under of Bernardino de Mendoza conquer Doetinchem |
| November 26 | Jacob of Necks merchant fleet reaches Bantam West-Java |