| February 25 | Portuguese garrison on Ambon surrenders to Admiral Van der Haghen |
| May 16 | Camillo Borghese elected to succeed Pope Leo XI becomes Paul V |
| June 10 | Valse Dimitri crowned Russian tsar for 1st time |
| August 18 | Spanish army under of general Spinola conquerors Lingen |
| October 3 | Chinese uprising on Philippines, Tondo/Quiapo massacre |
| October 27 | Spanish army under General Spinola occupies Wachtendonk |
| November 5 | Gunpowder Plot; Catholics try to blow up English Parliament. Plot uncovered and leader Guy Fawkes hanged |
