| February 19 | Trial against Johan van Oldenbarnevelt begins in The Hague |
| March 12 | Dutch settlement on Java changes name to Batavia |
| April 19 | Theatrum Anatomicum opens in Amsterdam |
| May 18 | Hugo the Great sentenced to life in prison |
| June 2 | England and Netherlands signs treaty about business in the Indies |
| June 24 | Tsar Michails father Filaret becomes patriarch of Moscow |
| July 20 | Gerardus Vossius resigns as Dutch regent States college leader |
| July 30 | House of Burgesses Virginia forms, 1st elective U.S. governing body |
| August 1 | 1st black Americans (20) land at Jamestown, Virginia |
| August 8 | Duke Maximilian I and Emperor Ferdinand II signs Treaty of Munchen |
| August 20 | 1st Black slaves brought by Dutch to colony of Jamestown Virginia |
| August 27 | Monarch Frederik van Palts chosen king of Bohemia |
| August 28 | Ferdinand II elected Holy Roman Emperor |
| September 15 | Prince Bethlen Gabors troops occupy Pozsony (Pressburg) Hungary |
| September 30 | Remonstrant Society forms in Antwerp |
| November 4 | Frederik V crowned king of Bohemia |
| December 4 | America's 1st Thanksgiving Day (Va) |