| January 7 | Composer Pier Cavalli marries rich widow Maria Sosomeno |
| January 13 | Patent to Plymouth Colony issued |
| February 14 | Dutch fleet of 69 ships reaches Pernambuco Brazil |
| February 22 | Indians introduce pilgrims to popcorn, at Thanksgiving |
| March 22 | 1st colonial legislation prohibiting gambling enacted (Boston) |
| March 23 | French troops occupy Pinerolo Piedmont |
| May 17 | Italian Jesuit Niccolo Zucchi, 1st to see 2 belts on Jupiter surface |
| May 29 | Governor John Winthrop begins "History of New England" |
| June 25 | Fork introduced to American dining by Governor Winthrop |
| June 26 | Swedish troops under Gustaf II Adolf lands at Peenemunde |
| July 3 | Emperor Ferdinand II opens German Parliament |
| July 6 | Swedish troops under Gustaf II Adolf land at Peenemunde |
| July 12 | New Amsterdam's governor buys Gull Island from Indians for cargo, renames it Oyster Island, it is later known as Ellis Island |
| July 18 | Spanish troops occupy Mantua |
| August 13 | Ferdinand II fires supreme commander Albrecht von Wallenstein |
| September 16 | Mass village of Shawmut changes name to Boston |
| October 19 | In Boston the 1st general court is held |
| November 5 | Spain and England sign peace treaty |
| November 10 | Failed palace revolution against Richelieu France |
| November 30 | 16,000 inhabitants of Venice died this month of plague |
