| January 14 | United East Indian Company conquerors city of Malakka, 7,000 killed |
| February 16 | English king Charles I accept Triennial Act |
| March 16 | General court declares RI a democracy and adopts new constitution |
| May 12 | Prince Willem II (14) marries English princess Henriette Mary Stuart (9) |
| June 1 | France and Portugal sign anti-Spanish covenant |
| July 6 | Battle at La Marfee Sedan: Earl Soisson beats French government army |
| July 27 | Prince Frederik Henry captures castle of Gennep |
| August 20 | Britain and Scotland sign Treaty of Pacification |
| August 26 | West India Company conquerors Sao Paulo de Loanda, Angola |
| October 15 | Paul de Chomedy de Maisonneuve claims Montreal |
| October 21 | Catholic uprising in Ulster: 1000s English and Scots killed |
| December 1 | Mass becomes 1st colony to give statutory recognition to slavery |
| December 6 | Don Francisco de Mello appointed land guardian of South Netherlands |
| December 25 | Emperor Ferdinand III makes appointments with Sweden and France |
