| January 25 | Czar Peter the Great ends Russian-orthodox patriarchy |
| March 9 | English Chancellor Exchequer John Aislabie confined in London Tower |
| March 24 | Johann Sebastian Bach opens his Brandenburgse Concerts |
| March 27 | France and Spain sign Treaty of Madrid |
| April 3 | Robert Walpole becomes England's 1st Lord of the Treasury |
| April 26 | Smallpox vaccination 1st administrated |
| May 8 | Michelangiolo dei Conti replaces Pope Clement XI, as Innocent XIII |
| May 25 | John Copson becomes America's 1st insurance agent |
| May 29 | South Carolina formally incorporated as a royal colony |
| June 13 | England signs Treaty of Madrid |
| June 26 | Dr. Zabdiel Boylston gives 1st smallpox inoculations in America |
| August 30 | Russian/Swedish Peace of Nystad, ends North Sea War |
| October 22 | Czar Peter the Great becomes "All-Russian Imperator" |
| November 1 | Prince Eugenius of Savoye unveals statue of himself |
