| January 23 | Armand-Gaston Camus becomes chairman of Council of 500 |
| February 29 | Jay's Treaty proclaimed, settles some differences with England |
| March 1 | 1st National Meeting in the Hague |
| March 9 | Napoleon Bonaparte marries Josephine de Beauharnais |
| March 28 | Bethel African Methodist Church of Philadelphia is 1st US-African church |
| March 31 | Johann Wolfgang von Goethes "Egmont," premieres in Weimar |
| April 13 | 1st elephant arrives in U.S. from India |
| April 13 | Battle at Millesimo Italy: Napoleon beats Austrians |
| April 22 | Napoleon defeats Piedmontese at Battle of Mondovi |
| April 28 | Cease fire of Cherasco |
| May 10 | French government arrest 10 utopists |
| May 10 | Napoleon defeats Austria in Battle of Lodi Bridge |
| May 10 | Riot after disagreement of patriotic demand in Amsterdam |
| May 14 | 1st smallpox inoculation administered, by Edward Jenner |
| May 15 | France and Sardinia sign Peace treaty of Paris |
| May 15 | French troops occupy Milan |
| May 16 | Lombardije Republic forms |
| May 19 | Game protection law restricts encroachment on Indian hunting grounds |
| May 27 | James S. McLean patents his piano |
| June 1 | Last of Britain's troops withdraws from U.S. |
| June 1 | Tennessee admitted as 16th U.S. state |
| July 4 | 1st Independence Day celebration is held |
| July 8 | U.S. State Department issues 1st American passport |
| July 22 | Cleveland, Ohio, founded by General Moses Cleaveland |
| August 8 | Boston African Society establishes with 44 members |
| August 17 | English beat Bataafs Navy in Saldanha Bay |
| August 19 | Spain and France sign anti-English alliance |
| August 23 | African Methodist Episcopal Church incorporated |
| September 2 | Jews of the Netherlands are emancipated |
| September 5 | General Salicetti orders equal rights for Jews of Bologna Italy |
| September 8 | Battle of Bassano-French beat Austrians |
| September 17 | President George Washington delivers his farewell address |
| September 19 | George Washington's farewell address as president |
| October 5 | Spain declares war on England |
| November 3 | John Adams elected president |
| November 17 | Battle of Arcole-Napolean I's French forces beat Austrians in Italy |
| December 18 | 1st U.S. newspaper to appear on Sunday (Baltimore Monitor) |