| January 9 | Income Tax introduced in UK |
| January 10 | Friedrich von Schiller's "Die Piccolomini," premieres in Weimar |
| January 14 | Eli Whitney receives government contract for 10,000 muskets |
| January 14 | King of Naples flees before advancing French armies |
| January 21 | Edward Jenner's smallpox vaccination is introduced |
| January 25 | 1st U.S. patent for a seeding machine, Eliakim Spooner, Vermont |
| February 9 | USS Constellation captures French frigate Insurgents off Nevis, W I |
| February 13 | 1st U.S. law regulating insurance passed, by Massachusetts |
| February 15 | 1st U.S. printed ballots authorized, Pennsylvania |
| February 25 | 1st federal forestry legislation authorizes purchase of timber land |
| February 25 | Congress passes 1st federal quarantine legislation |
| March 2 | Congress standardizes U.S. weights and measures |
| March 6 | Napolean captures Jaffa Palestine |
| March 12 | Austria declares war on France |
| March 19 | Joseph Haydn's "Die Schopfung," premieres in Vienna |
| March 26 | Napolean captures Jaffa Palestine |
| March 28 | New York State abolished slavery |
| April 14 | Napoleon called for establishing Jerusalem for Jews |
| April 20 | Friedrich von Schiller's "Wallensteins Tod," premieres in Weimar |
| April 20 | Napoleon issues a decree calling for establishing Jerusalem for Jews |
| June 22 | England and Russia decide to invade Bataafse Republic |
| July 24 | William Clark (of Lewis and Clark) is willed the slave York |
| July 25 | French-Egyptian forces under Napolean I beat Turks at Battle of Abukir |
| August 13 | English fleet under lord Seymour overthrows Suriname |
| August 27 | English invasion army lands in North-Holland |
| August 30 | Bataafse fleet surrender to English |
| September 1 | Bank of Manhattan Company opens in New York City (forerunner to Chase Manhattan) |
| September 19 | English and Russian invasion army conquerors Receiver |
| October 2 | Duke of York and Russians capture Alkmaar in Netherlands |
| October 6 | Battle at Castricum: French and Bataafs army beats English/Russian army |
| October 9 | British frigate HMS Lutine sinks off Dutch coast |
| October 10 | Convention of Alkmaar: English/Russian invasion army departs |
| October 22 | Russia leaves second anti-French Coalition |
| November 9 | Napoleon becomes dictator (1st consul) of France |
| December 10 | Metric system established in France |
| December 18 | George Washington's body interred at Mount Vernon |
| December 24 | Jakobijns plot against Napoleon uncovered |
| December 26 | George Washington is eulogized by Col Henry Lee as "1st in war, 1st in peace and 1st in hearts of his countrymen" |