| January 11 | 1st pineapples planted in Hawaii (or 1/21) |
| January 14 | Gideon Hawley becomes 1st state school superintendent in U.S. (NY) |
| January 21 | Pineapple introduced to Hawaii |
| January 22 | Americans capture Frenchtown, Canada |
| February 23 | 1st U.S. raw cotton-to-cloth mill founded in Waltham, Massachusetts |
| February 27 | 1st federal vaccination legislation enacted |
| February 27 | Congress authorizes use of steamboats to transport mail |
| March 3 | Office of surgeon general of the U.S. Army forms |
| March 8 | 1st concerto of Royal Philharmonic |
| March 18 | David Melville, Newport, Rhode Island, patents apparatus for making coal gas |
| March 25 | 1st U.S. flag flown in battle on the Pacific, frigate Essex |
| April 27 | Americans under General Pike capture Toronto; Pike is killed |
| April 29 | Rubber is patented |
| May 27 | Americans capture Ft. George, Canada |
| June 1 | Captain John Lawrence utters Navy motto "Don't give up the ship" |
| June 6 | U.S. invasion of Canada halted at Stoney Creek |
| June 24 | Battle of Beaver Dam-British and Indian forces defeat U.S. forces |
| July 31 | British invade Plattsburgh, New York |
| August 14 | British warship Pelican attacks and captures U.S. war brigantine Argus |
| August 23 | Battle of Grossbeeren - Prussians under Von Bulow repulse French |
| August 27 | Battle of Dresden-Napoleon defeats Austrians |
| September 4 | 1st U.S. relig newspaper (Religious Remembrancer (Christian Observer)) |
| September 7 | "Uncle Sam" was 1st used to refer to U.S. (Troy Post of New York) |
| September 10 | Comm Oliver H Perry defeats British in Battle of Lake Erie |
| October 5 | Battle of Thames in Canada; Americans defeat British |
| October 8 | Treaty of Ried between Bayern and Austria |
| October 16 | Battle at Leipzig (Napoleon vs Prussia, Austria and Russia) |
| October 20 | German Kingdom of Westphalia abolished |
| November 2 | Treaty of Fulda |
| November 3 | U.S. troops under General Coffee destroy indian village at Talladega Ala |
| November 6 | Chilpancingo congress declares Mexico independent of Spain |
| November 11 | Dresden surrenders to allied armies |
| November 12 | Allied troops occupy Zwolle, Netherlands |
| November 15 | Allied troops occupies Groningen |
| November 15 | Tax revolt in Amsterdam |
| November 21 | Stettin surrenders to allied armies |
| November 28 | Kosacks occupy Utrecht |
| November 29 | Elias Canneman (Lib) becomes minister of Finance |
| November 30 | Prince Willem Frederik returns to Netherlands |
| December 2 | Prince Willem Frederik accepts constitutional monarchy |
| December 5 | Lubeck surrenders to allied armies |
| December 8 | Ludwig von Beethoven's 7th Symphony in A, premieres |
| December 18 | British take Ft. Niagara in War of 1812 |
| December 26 | Zamose, Modlin, Torgau surrenders to allied armies |
| December 29 | British burn Buffalo, New York during War of 1812 |
| December 30 | Danzig surrenders to allied armies |