| January 12 | France decrees Bonaparte family excluded from the country forever |
| January 22 | Lord Byron completes "Parisina" and "Siege of Corinth" |
| February 5 | Rossini's Opera "Barber of Seville," premieres in Rome |
| February 13 | Teatro San Carlo in Naples destroyed by fire |
| February 20 | Rossini's opera "Barber of Seville" premieres in Rome |
| February 27 | Dutch regain Suriname |
| February 29 | Dutch King Willem II marries Russian grand-duchess Anna Paulowna |
| March 6 | Jews are expelled from Free city of Lubeck Germany |
| March 20 | U.S. Supreme Court affirms its right to review state court decisions |
| April 9 | African Methodist Episcopal Church organizes in Philadelphia |
| April 10 | 2nd Bank of U.S. chartered |
| May 5 | American Bible Society organized in New York |
| May 10 | English steamship "Defiance" arrives at Rotterdam harbor |
| May 11 | American Bible Society forms in New York |
| June 6 | 10" snowfall in New England, "year without a summer", from the eruption of Mount Tambora in Indonesia |
| June 11 | Gas Light Co of Baltimore founded |
| July 1 | French frigate Medusa wrecked; basis of Gericault's "Raft of the Medusa" |
| July 3 | French frigate "Medusa" runs aground off Cap Blanc. Gross incompetence kills 150 in calm seas |
| July 8 | Frost in Waltham, Massachusetts |
| July 9 | Argentina declares independence from Spain |
| July 19 | Survivors of French frigate Medusa rescued off Senegal after 17 days |
| July 27 | U.S. troops destroy Ft. Apalachicola, a Seminole fort, to punish Indians for harboring runaway slaves |
| August 8 | Bavarian joins Saint Alliance |
| August 14 | Great Britain annexes Tristan da Cunha |
| August 19 | Java again in Dutch hands |
| August 27 | Lord Exmouth bombs Algiers, a refuge for Barbary pirates |
| October 7 | 1st double decked steamboat, Washington, arrives in New Orleans |
| December 2 | 1st savings bank in U.S. opens (Philadelphia Savings Fund Society) |
| December 4 | James Monroe (VA), elected 5th president, defeating Federalist Rufus King |
| December 10 | Dutch regain Sumatra |
| December 11 | Citizens of Geneva thwarted Savoyard invaders |
| December 11 | Indiana becomes 19th state |
| December 13 | Patent for a dry dock issued to John Adamson, Boston |
| December 28 | American Colonization Society organizes |