| January 12 | Royal Astronomical Society founded in England |
| January 30 | Edward Bransfield aboard Williams discovers Antarctica (UK claim) |
| February 6 | 1st organized emigration of blacks back to Africa (New York to Sierra Leone) |
| February 6 | U.S. population announced at 9,638,453 (1,771,656 blacks (18.4%)) |
| February 23 | Cato Street conspiracy uncovered |
| March 3 | Missouri Compromise passes, allowing slavery in Missouri |
| March 5 | Dutch city of Leeuwarden forbids Jews to go to synagogues on Sundays |
| March 9 | James Monroe's daughter Maria marries in the White House |
| March 9 | Philippines chases out foreigners; about 125 die |
| March 15 | Maine admitted as 23rd state |
| March 25 | Greece freedom revolt against anti Ottoman attack |
| May 13 | Opera "Die Jagarsbraut" is completed |
| June 28 | Tomato is proven non-poisonous |
| July 1 | 1st edition of newspaper "Courrier de la Meuse" published" |
| August 7 | 1st potatoes planted in Hawaii |
| August 14 | 1st U.S. eye hospital, the New York Eye Infirmary, opens in New York City |
| October 9 | Guayaquil, Ecuador declares its freedom from Ecuador |
| October 20 | Spain sells part of Florida to U.S. for $5 million |
| November 3 | Cuenca Ecuador declares independence |
| November 7 | James Monroe elected 5th U.S. president |
| November 17 | Antarctica discovered by Nathaniel B. Palmer on the 'Hero', a 47 foot sloop |
| December 6 | U.S. president James Monroe re-elected |
| December 15 | 1st General pharmacopoeia in U.S. published, Boston |
| December 20 | Missouri imposes a $1 bachelor tax on unmarried men between 21 and 50 |
BrainyHistory
