| January 19 | Johann von Goethe's "Faust, Part 1," premieres |
| February 2 | Madman Jonathan Martin sets York Cathedral afire, does 60,000 pounds damage |
| March 2 | New England Asylum for the Blind, 1st in U.S., incorporated, Boston |
| March 4 | Andrew Jackson inaugurated as 7th president |
| March 4 | Unruly crowd mobs White House during President Jackson inaugural ball |
| March 16 | Ohio authorizes high school night classes |
| April 9 | Danzig (Gdansk) dike break flood kills 1,200 |
| April 13 | English Emancipation Act grants freedom of religion to Catholics |
| April 28 | Dutch parliament accepts new press laws |
| May 15 | Joseph Smith ordained by John the Baptist according to Joseph Smith |
| May 24 | Pope Pius VIII issues his program for pontificate |
| June 8 | 1st U.K. municipal swimming pool outside of London, opens in Liverpool |
| June 19 | Sir Robert Peel found London Metropolitan Police (Bobbies) |
| July 4 | Cornerstone laid for 1st U.S. mint (Chestnut and Juniper St, Philadelphia) |
| July 7 | Royal Military Chapel forms |
| July 23 | William Austin Burt patents "typographer" (typewriter) |
| August 3 | Gioacchino Rossini's "William Tell," premieres in Paris |
| August 8 | French government of De Polignac forms |
| August 9 | "Stourbridge Lion" locomotive goes into service |
| August 16 | Siamese twins Chang and Eng Bunker arrive in Boston to be exhibited |
| August 25 | President Jackson makes an offer to buy Texas, but Mexican government refuses |
| August 31 | Opera "Guillaume Tell" is produced (Paris) |
| September 14 | Peace of Adrianopel: ends Russian-Turkish war |
| September 24 | Russia and Ottoman Empire sign Peace Treaty of Adrianople |
| September 25 | Failed assassination attempt on Simon Bolivar |
| September 28 | Walker's Appeal, racial antislavery pamphlet, published in Boston |
| September 29 | London's Metropolitan Police Force goes on duty (Scotland Yard) |
| October 16 | Tremont Hotel, 1st U.S. modern hotel opens (Boston) |
| October 17 | Delaware River and Chesapeake Bay Canal formally opens |
| October 17 | German 1st assassination on abandoned teenager Kaspar Hauser |
| November 20 | Jews expelled from Nikolayev and Sevastopol Russia |
| December 4 | Britain abolished "suttee" in India, widow burning herself to death on her husband's funeral pyre |
| December 21 | 1st stone arch railroad bridge in U.S. dedicated, Baltimore |
