| January 7 | 1st U.S. Railroad Station opens (Baltimore) |
| January 8 | Dutch King Willem I fires him displeasing parliament members |
| January 13 | Great fire in New Orleans thought to be set by rebel slaves |
| January 21 | Portsmouth (Ohio) blacks forcibly deported |
| January 28 | Opera "Fra Diavolo," premieres in Paris |
| February 25 | Victor Hugo's "Hernani" premieres in Paris |
| March 4 | V Bellini's opera "I Capuleti e i Montecchi," premieres in Venice |
| March 16 | London's re-organised police force (Scotland Yard) |
| March 16 | New York Stock Exchange slowest day ever (31 shares traded) |
| April 6 | Joseph Smith and 5 others organizes Mormon church in Seneca Co, New York |
| April 11 | Robert Schumann attends piano concerto by Paganini |
| May 3 | 1st regular steam train passenger service starts |
| May 13 | Republic of Ecuador is founded, with Juan Jose Flores as president |
| May 18 | Edwin Budding of England signs an agreement for manufacture of his invention, lawn mower. Saturdays are destroyed forever |
| May 20 | 1st railroad timetable published in newspaper (Baltimore American) |
| May 20 | D. Hyde patents fountain pen |
| May 24 | 1st passenger rail service in U.S. (Baltimore and Elliots Mill, Maryland) |
| May 24 | "Mary Had A Little Lamb," is written |
| May 28 | Congress authorizes Indian removal from all states to western prairie |
| July 5 | France invades Algeria, begins a 40 year conquest |
| July 15 | 3 Indian tribes, Sioux, Sauk and Fox, signs a treaty giving the U.S. most of Minnesota, Iowa and Missouri |
| July 27 | Revolution breaks out in Paris, opposing laws of Charles X |
| July 28 | Revolution in France replaces Charles X with Louis Philippe |
| July 31 | Charles X of France resigns by force |
| August 4 | Plans for city of Chicago laid out |
| August 9 | Louis-Philippe formally accepts crown of France, following abdication of Charles X |
| August 25 | Belgium revolts against Netherlands |
| August 28 | 1st locomotive in U.S., "Tom Thumb," runs from Baltimore to Ellicotts Mill |
| September 9 | Charles Durant, 1st U.S. aeronaut, flies a balloon from Castle Garden, New York City to Perth Amboy, NJ |
| September 14 | Princess WFLC Marianne marries Albrecht of Prussia |
| September 15 | 1st to be run-over by a railroad train (William Huskisson, England) |
| September 15 | Duke of Wellington opens Liverpool and Manchester Railway |
| September 16 | Oliver Wendell Holmes writes "Old Ironsides" |
| September 18 | Horse beats 1st U.S. made locomotive (near Baltimore) |
| September 23 | Dutch troops occupy Brussels |
| September 27 | Dutch army leaves Brussels, after 100s killed |
| October 1 | General Trade Journal newspaper begins publishing in Amsterdam |
| October 4 | Provisional government declares secession of Belgium from Netherlands |
| October 5 | King Willem I mobilizes Dutch army |
| October 26 | Belgian rebels occupy Antwerp |
| October 27 | Major-General Baron D Chasse bombs Antwerp (Belgium revolution) |
| November 13 | Oliver Wendell Holmes publishes "Old Ironsides" |
| December 5 | Hector Berlioz' "Symphonique fantastique," premieres in Paris |
| December 20 | England, France, Prussia, Austria and Russia recognize Belgium |
| December 25 | Hector Berlioz's "Symphony Fantastic," premieres |
| December 26 | Gaetano Donizetti's opera "Anna Bolena," premieres in Milan |
