| January 1 | Simpson-Hayward (England) takes 6-43 on debut with underarm lobs |
| January 2 | 1st junior high schools in U.S. opens (Berkeley California) |
| January 3 | British miners strike for 8 hour working day |
| January 7 | Stanley Cup: Ottawa Senators sweep Galt (Ont) in 2 games |
| January 10 | 1st international air meet in U.S. held, in LA |
| January 10 | Lunt-Fontanne Theater (Globe) opens at 205 W 46th St. New York City |
| January 13 | JM Synge's "Deirdre of the Sorrows," premieres in Dublin |
| January 19 | Germany and Bolivia ends commerce/friendship treaty |
| January 19 | National Institute of Arts and Letters incorporated by Congress |
| January 20 | Ottawa Senators sweep Edmonton in 2 for Stanley Cup (2nd of 1910) |
| January 21 | British-Russian military intervention in Persia |
| January 22 | Opera "Germania," premieres in New York City |
| January 25 | 1st stumping by a 12th man in Tests (N C Tufnell, SAf vs. Eng) |
| January 25 | Children initiate idea of planting trees in Jerusalem |
| January 26 | Heavy rains cause floods in Paris |
| February 1 | 1st British labour exchange opens |
| February 1 | Dragoumis government forms in Greece |
| February 7 | Edmond Rostand's "Chantecler," premieres in Paris |
| February 8 | Boy Scouts of America incorporated and chartered (William D. Boyce - Chicago) |
| February 19 | English premiere of Richard Strauss' "Elektra" |
| February 21 | John Galsworthy's "Justice," premieres in London |
| February 23 | 1st radio contest held (Philadelphia) |
| February 23 | George Bernard Shaw's "Misalliance," premieres in London |
| February 25 | Dali Lama flees Tibet from Chinese troop to British-Indies |
| March 1 | 3 passenger trains buried at Steven's Pass in Cascade Range. 118 die. Worst snow slide in U.S. history |
| March 2 | 2 trains crash in snow storm in Wellington Washington, 118 die |
| March 5 | Ramon Inclan's "La Farsa Infantil de la Cabeza del Dragon," premieres |
| March 5 | Stanley Cup: Montreal Wanderers beat Ottawa Senators, 3-1 |
| March 8 | Baroness Raymonde de Laroche of Paris is 1st licensed female pilot |
| March 10 | China ends slavery |
| March 10 | Pittsburgh Courier, begins publishing |
| March 11 | Jack Hobbs 1st Test ton (187 vs. SAfr), his only Test hit wicket |
| March 12 | Stanley Cup: Montreal Wanderers beat Berlin (Kitchener), 7-3 |
| March 16 | Barney Oldfield sets land speed record of 131.7 mph at Daytona |
| March 17 | DHC soccer team forms in Delft, Netherlands |
| March 18 | 1st opera by an U.S. composer (Converse) performed at the Met, New York City |
| March 23 | 1st race at Los Angeles Motordrome (1st U.S. auto speedway) |
| March 24 | 83 degrees F highest temperature ever recorded in Cleveland in March |
| March 25 | Chalmers Auto Co offers a new car to each leagues' batting champ |
| March 26 | U.S. forbid immigration to criminals, anarchists, paupers and the sick |
| March 26 | William H. Lewis appointed asst attorney general of U.S. |
| March 28 | 1st seaplane, takes off from water at Martinques France (Henri Fabre) |
| April 1 | Dumitru Dan (Romania) completes a 62,137 mile (100,000 m) walk |
| April 3 | Highest mountain in North America, Alaska's Mount McKinley climbed |
| April 14 | President Taft begins tradition of throwing out ball on opening day |
| April 15 | Taft is 1st President to throw out a 1st ball at a baseball game |
| April 19 | 14th Boston Marathon won by Fred Cameron of Canada in 2:28:52.4 |
| April 19 | Halley's comet seen by naked eye 1st time this trip (Curacao) |
| April 20 | Cleveland Indians Addie Joss 2nd no-hitter, beats Chicago, 1-0 |
| April 20 | Halley's Comet passes 29th recorded perihelion at 87.9 million km |
| April 21 | Cleveland Naps play 1st game at League Park, lose to Det Tigers 5-0 |
| April 23 | International Exhibition opens in Brussels |
| April 24 | German Catholic youth movement Quickborn forms |
| April 27 | Belgian parliament rejects socialist motion for general voting rights |
| April 28 | 1st night air flight (Claude Grahame-White, England) |
| April 29 | Ex-president Theodore Roosevelt visits Amsterdam |
| April 30 | Cleveland Indian Addie Joss wins 2nd no-hitter beating White Sox |
| May 4 | Canadian Currency Act, 1910, receives Royal Assent |
| May 4 | Canadian parliament accept creation of Royal Canadian Navy |
| May 4 | Tel Aviv founded |
| May 6 | King George V ascends to British throne |
| May 7 | 35th Preakness: R Estep aboard Layminster wins in 1:40.6 |
| May 10 | 1st aircraft air display held (Hendon, England) |
| May 10 | 36th Kentucky Derby: Fred Herbert aboard Donau wins in 2:06.4 |
| May 10 | Comet Halley's closest approach to Earth in 1910 pass |
| May 11 | Montana's Glacier National Park forms |
| May 12 | 2nd NAACP conference (New York City) |
| May 12 | Phil A's Chief Bender no-hits Cleveland Indians, 4-0 |
| May 14 | Canada authorizes issuing of silver dollar coins |
| May 16 | U.S. Bureau of Mines forms |
| May 17 | Canada sets the designs for the 1 cent -50 cent coins |
| May 18 | Passage of Earth through tail of Halley's Comet causes near-panic |
| May 19 | Cleveland Indian Cy Young gets his 500th win, beats Washington 5-4 in 11 innings |
| May 20 | Funeral for Britain's King Edward VII |
| May 29 | Pope's encyclical on Editae Saepe, against church reformers |
| May 30 | 44th Belmont: James Butwell aboard Sweep wins in 2:22 |
| May 31 | Cape of Good Hope becomes part of Union of South Africa |
| May 31 | Glenn Curtiss flies from Albany to New York City |
| May 31 | Union of South Africa declares independence from U.K. |
| June 1 | South Carolina Enschede soccer team forms in Enschede |
| June 2 | 1st roundtrip flight over English Channel, C S Rolls, England |
| June 2 | Pygmies discovered in Dutch New Guinea |
| June 9 | Passenger on SS Arawatta throws bottle with note overboard, found June 6, 1983 in Queensland |
| June 12 | PEC soccer team forms in Zwolle |
| June 13 | Pilot Charles Hamilton makes 1st 1-day round-trip from New York to Philadelphia |
| June 13 | William D. Crum, a South Carolina physician, appointed minister to Liberia |
| June 18 | 16th U.S. Golf Open: Alex Smith shoots a 298 at Philadelphia Cricket Club PA |
| June 19 | 1st airship in service "Germany" |
| June 19 | Father's Day celebrated for 1st time (Spokane, Wash) |
| June 20 | "Krazy Kat" comic strip by George Herriman debuts in New York Journal |
| June 22 | 1st Zeppelin with passengers sets afloat |
| June 24 | 50th British Golf Open: James Braid shoots a 299 at St. Andrews Scot |
| June 25 | Mann Act passed (no women across state lines for immoral purposes) |
| June 26 | 24th U.S. Womens Tennis: H Hotchkiss Wightman beats L Hammond (64 62) |
| June 26 | Hazel Hotchkiss wins U.S. Lawn Tennis Association championship |
| June 30 | Russia absorbs Finland |
| July 1 | Chicago's Comiskey Park opens - St. Louis Browns beat White Sox 2-0 |
| July 1 | Union of South Africa becomes a dominion |
| July 1 | White Sox Park (Comiskey Park) opens with 2-0 loss to Browns |
| July 4 | Jack Johnson KOs James J Jeffries in 15 for heavyweight boxing title |
| July 9 | Walter Brookins becomes 1st to pilot an airplane to 1 mile altitude |
| July 10 | Chicago White Sox Comiskey Park opens, visiting Browns win 2-0 |
| July 19 | Cy Young registers his 500th career victory |
| July 20 | Former Dutch premier Abraham Kuyper acquitted of corruption |
| July 24 | Matador Juan Belmonte (18) kills his 1st bull |
| July 29 | JWEL Hilgers is 1st Dutchman to fly above Dutch territory |
| July 31 | Chicago Cub King Cole no-hits St. Louis, 4-0 in a 7 inning game |
| July 31 | Clement van Maasdijk gives flying demonstration |
| August 4 | A's Jack Coombs and White Sox Ed Walsh pitch a 16 inn scoreless tie |
| August 6 | New York City Mayor Wm J Gaynor seriously wounded during assassination attempt |
| August 9 | Alva Fisher patents electric washing machine |
| August 13 | Dodgers and Pirates play to 8-8 tie, both have 38 at bats, 13 hits, 12 assists, 2 errors, 5 strikeouts, 3 walks, 1 pass ball and 1 hit by pitch |
| August 14 | 6th International Congress of Esperantists held in Washington, D.C. |
| August 20 | U.S. supported opposition brings down Madriz in Nicaragua |
| August 22 | Japan annexes Korea after 5 years as a protectorate |
| August 23 | Fred Clarke makes a record 4 outfield assists for Pittsburgh |
| August 25 | 30th U.S. Mens Tennis: Wm Larned beats Thomas Bundy (61 57 60 68 61) |
| August 27 | Using 20, 137,000 candlepower arc lights, 2 amateur baseball teams play a night game at White Sox Park |
| August 27 | Washington Red Killefer sacrifices record 4 times against Detroit |
| August 30 | Yank Tom Hughes pitches 9 no-hit innings but loses to Cleveland 5-0 in 11 |
| September 5 | Jack Coombs begins a record streak of 53 shutout innings |
| September 6 | Saskatchewan (then Regina) Roughrider football club formed |
| September 10 | Great Idaho Fire destroys 3 million acres of timber |
| September 11 | 1st commercially successful electric bus line opens (Hollywood) |
| September 12 | Gustav Mahlers 8th Symphony premieres in Munich with 1028 musicians |
| September 12 | World's 1st female cop, Alice Stebbins Wells, appointed (LAPD) |
| September 13 | Regina Rugby Club forms |
| September 15 | Boers and Afrikaners win 1st general elections in Union of South Africa |
| September 18 | 25,000 demonstrate in Amsterdam for general male/female suffrage |
| September 19 | George Cohan's "Get-Rich-Quick Wallingford," premieres in New York City |
| September 22 | England's 1st aircraft flight |
| September 22 | Saskatchewan Rugby Football Union forms |
| September 27 | 1st test flight of a twin-engined airplane (France) |
| October 1 | Berkshire Cattle Fair held in Pittsfield Mass (1st state fair) |
| October 1 | Explosion at Los Angeles Times kills 21 |
| October 1 | Regina Rugby Club's 1st game, losing to Moose Jaw Tigers, 16-6 |
| October 2 | 1st 2 aircraft collision (Milan Italy) |
| October 2 | Henry Wijnmalen flies to 2,800m altitude (world record) |
| October 4 | Portugal becomes a republic, King Manuel II flees to England |
| October 5 | Portugal overthrows monarchy, proclaims republic |
| October 6 | Braves beat Phillies 20-7 |
| October 9 | Nap Lajorie challenges Ty Cobb batting avg with 8 hits, 6 were bunts as Brown's 3rd baseman Red Corriden played deep, Cobb still won |
| October 18 | Edward Forster publishes "Howards End" |
| October 20 | 1st appearance of cork centered baseball in World Series |
| October 20 | Soccer team KFC forms in Alkmaar |
| October 23 | Blanche Scott became 1st woman solo a public airplane flight |
| October 23 | Philadelphia A's beat Chicago Cubs 4 games to 1 in 7th World Series |
| October 23 | Ritz Hotel in Madrid opens: 200 chambers/100 bathtubs |
| October 29 | Bob Simpson of Hamilton Tigers kicks record 11 singles in a game |
| November 1 | 1st issue of "Crisis" published by editor W E B Du Bois |
| November 4 | Start of South Africa's 1st F-C game in Australia (vs. South Australia) It rained |
| November 6 | SDAP/NVV initiate campaign for general males/female suffrage |
| November 8 | 1st Washington State election in which women could vote |
| November 12 | 1st Movie stunt: man jumps into Hudson river from a burning balloon |
| November 14 | 1st airplane flight from deck of a ship, Norfolk, Va |
| November 19 | Ferenc Moln rs "Tester," premieres in Budapest |
| November 20 | Revolution broke out in Mexico, led by Francisco I Madero |
| November 22 | Arthur Knight patents steel shaft golf clubs |
| November 26 | 2nd CFL Grey Cup: University of Toronto defeats Hamilton Tigers, 16-7 |
| November 27 | New Yorks's Penn Station opens as world's largest train station |
| December 3 | Neon lights, 1st publically seen (Paris Auto Show) |
| December 9 | French troops occupy Morrocan harbor city Agadir |
| December 10 | JD Van de Waals wins Nobel Prize for physics |
| December 19 | 1st city ordinace requiring white and black residential areas (Balt) |
| December 19 | Rayon 1st commercially produced, Marcus Hook, Penn |
| December 21 | Explosion in coal mine in Hulton England, 344 mine workers dies |
| December 22 | U.S. postal savings stamps 1st issued |
| December 24 | Luisa Tetrazzini sings to 250,000 people at Lotta's Fountain |
| December 28 | Opera "Konigskinder" is produced (New York City) |
| December 31 | U.S. tobacco industry produced 9 billion cigarettes in 1910 |
