| January 2 | 1st religious service radio broadcast in U.S., KDKA-Pittsburgh |
| January 2 | DeYoung Museum in Golden Gate Park opens |
| January 3 | Turkey makes peace with Armenia |
| January 4 | Eugene O'Neill's "Diff'rent," premieres in New York City |
| January 12 | Kenesaw Mountain Landis becomes 1st commissioner of baseball |
| January 18 | William Archer's "Green Goddess," premieres in New York City |
| January 19 | Costa Rica, Guatemala, Honduras and El Salvador sign Pact of Union |
| January 20 | British submarine K5 leaves with man and mouse |
| January 20 | Dagestan ASSR forms in RSFSR |
| January 20 | Mountain Autonomous Republic established in RSFSR |
| January 20 | Turkey declared in remnants of Ottoman Empire |
| January 25 | Karel Capek's "RUR," premieres in Prague |
| January 26 | Soccer team GVAV of Groningen Netherlands forms |
| January 26 | Toronto St. Pat Corb Denneny scores 6 goals vs Hamilton Tigers |
| January 29 | Hurricane hits Washington and Oregon |
| February 5 | Yankees purchase 20 acres in Bronx for Yankee Stadium |
| February 6 | "The Kid," starring Charlie Chaplin and Jackie Coogan, released |
| February 11 | Ambassador Theater opens at 215 W 49th St. New York City |
| February 12 | Soviet troops invade Georgia |
| February 12 | Winston Churchill becomes British, minister of Colonies |
| February 14 | Canadian 5 cent nickel coin is authorized |
| February 14 | Little Review faces obscenity charges for publishing "Ulysses," NY |
| February 15 | Arthur Mailey completes 9-121 vs. England, Australian Test Cricket rec |
| February 17 | Arthur Honegger's "Pastorale D'ete," premieres |
| February 18 | British troops occupy Dublin |
| February 20 | Riza Khan Pahlevi seizes control of Iran |
| February 23 | 1st U.S. transcontinental air mail flight arrives in New York City from San Francisco |
| February 24 | 1st transcontinental flight in 24 hours flying time arrives Florida |
| February 25 | Georgian SSR proclaimed |
| February 27 | U.S. Female Figure Skating championship won by Theresa Weld Blanchard |
| February 27 | U.S. Male Figure Skating championship won by Sherwin Badger |
| March 1 | Australia Cricket team complete 5-0 drubbing of England |
| March 1 | Rwanda ceded to England |
| March 1 | Sailors revolt in Kronstadt Russia |
| March 3 | Toronto's Dr. Banting and Dr. Best announce discovery of insulin |
| March 4 | Hot Springs National Park created in Arkansas |
| March 6 | Police in Sunbury Penn issue an edict requiring Women to wear skirts at least 4 inches below the knee |
| March 7 | Red Army under Trotsky attack sailors of Kronstadt |
| March 13 | Mongolia (formerly Outer Mongolia) declares independence from China |
| March 17 | Dr. Marie Stopes opens Britain's 1st birth control clinic (London) |
| March 17 | Lenin proclaims New Economic Politics |
| March 17 | Sailors revolt in Kronstadt (thousands die) |
| March 18 | 2nd Peace of Riga, Poland enlarged |
| March 18 | Steamer "Hong Koh" runs aground off Swatow China killing 1,000 |
| March 21 | Walter Kerr Theater (Ritz, CBS, NBC, ABC) opens at 223 W 48th St. New York City |
| March 31 | Albert Einstein lectures in New York on his new theory of relativity |
| March 31 | British coal miners goes on strike |
| April 2 | Albert Einstein lectures in New York City on his new theory of relativity |
| April 4 | Stanley Cup: Ottawa Senators (NHL) beat Vancouver Millionaires (PCHA), 3 games to 2 |
| April 11 | Iowa imposed 1st state cigarette tax |
| April 11 | KDKA broadcast 1st radio sporting event, a boxing match (Ray-Dundee) |
| April 11 | Turkestan ASSR forms in Russian SFSR |
| April 14 | NHL Championship: Ottawa Senators sweep Toronto St. Patricks in 2 games |
| April 14 | Prince Henry opens Rotterdam-Amsterdam-Bremen-Hamburg air route |
| April 15 | Black Friday- Labour Party strike of mine workers fails |
| April 16 | Liberal Freedom League forms in The Hague |
| April 18 | Junior Achievement incorporated in Colorado Springs Colo |
| April 18 | Philip James Barry's "Punch for Judy," premieres in New York City |
| April 19 | 25th Boston Marathon won by Frank Zuna of New Jersey in 2:18:57.6 |
| April 19 | Funeral of last German Emperoress, Augusta Victoria |
| April 23 | Charles Paddock runs world record 100m (10.4 seconds) |
| April 24 | 1st municipal elections for men and women in Belgium |
| April 27 | Hadjememaar, [Corn de Gelder] elected in Amsterdam |
| April 30 | American Professional Football Association reorganizes in Akron |
| April 30 | Pope Benedict XV encyclical "On Dante" |
| May 1 | Drusian sultan Pasja al-Atrasj elected governor of Suwayda |
| May 2 | Begin 3rd anti-German revolt in Upper-Silesia |
| May 3 | West Virginia imposes 1st state sales tax |
| May 5 | 1st ranger for Cleveland Metroparks hired |
| May 5 | Miniature newspaper published (Brighton Gazette 10 x 13 cm) |
| May 6 | American Soccer League forms |
| May 7 | 47th Kentucky Derby: Charles Thompson on Behave Yourself wins 2:04.2 |
| May 8 | Sweden abolished capital punishment |
| May 10 | Luigi Pirandello's "Sei Personaggi in Cerca d'Autore," premieres |
| May 11 | Tel Aviv is 1st all Jewish municipality |
| May 12 | National Hospital Day 1st observed |
| May 14 | Florence Allen is 1st woman judge to sentence a man to death |
| May 14 | Mussolini's fascists obtains 29 parliament seats |
| May 16 | 47th Preakness: F Coltiletti aboard Broomspun wins in 1:54.2 |
| May 17 | Belgian-Luxembourg sign customs union |
| May 17 | President Harding opens (via telephone) 1st Valencia Orange Show |
| May 19 | Congress sharply curbs immigration, setting a national quota system |
| May 21 | Oldest radio station west of Mississippi River licensed in Greeley Co |
| May 23 | "Shuffle Along" 1st black musical comedy, opens in New York City |
| May 24 | 1st parliament for Northern Ireland elected |
| May 24 | British Legion forms |
| May 27 | After 84 years of British control, Afghanistan achieves sovereignty |
| May 30 | Lord Dunsany's "If," premieres in London |
| May 30 | Memorial to Captain Eddie Grant, killed in WW I, unveiled at Polo Grounds |
| May 30 | Salzburg, Austria, votes to join Germany |
| May 31 | Suffy McInnis (1st base) begins an errorless string of 1,700 |
| June 1 | Race riot in Tulsa, Oklahoma, 61 people killed |
| June 3 | A sudden cloudburst kills 120 near Pikes Peak, Colorado |
| June 8 | Babe Ruth arrested for speeding, fined $100, and held in jail until 4 PM |
| June 10 | Babe Ruth becomes all time HR champ with #120, Gavvy Cravath |
| June 11 | 53rd Belmont: Earl Sande aboard Grey Lag wins in 2:16.8 |
| June 11 | Brazil adopts women suffrage |
| June 13 | Yankees' pitcher Babe Ruth hits 2 home runs beating Tigers 11-8 |
| June 15 | Bessie Coleman reaches France as U.S. 1st black pilot |
| June 19 | Turk and Christian of Palestine sign a friendship treaty against Jews |
| June 20 | 11.5" (29.2 cm) of rainfall, Circle, Montana (state record) |
| June 21 | HSC '21 soccer team forms in Haaksbergen |
| June 22 | Paavo Nurmi runs world record 10,000m (30:40.2) |
| June 25 | 56th British Golf Open: Jock Hutchison shoots a 296 at St. Andrews |
| June 25 | Charlie McCartney scores 300 in 205 minutes Australia vs. Notts |
| June 29 | 34th Wimbledon Womens Tennis: Suzanne Lenglen beats E Ryan (62 60) |
| July 2 | 41st Wimbledon Mens Tennis: B Tilden beats B Norton (46 26 61 60 75) |
| July 2 | Jack Dempsey KOs George S Carpentier in 4 for heavyweight boxing title 1st million dollar gate ($1.7m) boxing match (Dempsey KOs Carpentier) |
| July 11 | Mongolia gains independence from China (National Day) |
| July 12 | Babe Ruth sets record of 137 career home runs |
| July 12 | Indians (9) and Yankees (7) combine for an AL record 16 doubles |
| July 14 | Nicola Sacco and Bartolomeo Vanzetti convicted in Dedham Massachusetts, of killing their shoe company's paymaster |
| July 18 | Black Sox trial begins in Chicago |
| July 21 | Indians (9) and Yankees (7) hit a record 16 doubles |
| July 22 | 25th U.S. Golf Open: Jim Barnes shoots a 289 at Columbia CC in MD |
| July 23 | Chinese Communist Party forms under Henk Sneevliet |
| July 23 | Edward Gourdin of U.S., sets then long jump record at 25' 2 3/4" |
| July 24 | Belgium's Leon Scieur wins Tour de France |
| July 27 | 2nd government of Ruijs de Beerenbrouck forms |
| July 27 | Frederick Banting and Charles Best isolates insulin at University of Toronto |
| July 29 | Cleveland's 125th anniversary celebration: Cy Young, 54, pitches 2 inn |
| July 29 | New rules of language assumed, equal rights Flemings/Walen Belgium |
| August 2 | Chicago jury brings in not guilty verdict against the Black Sox |
| August 3 | 1st aerial cropdusting (Troy Ohio to kill caterpillars) |
| August 3 | Due to a technicality, 8 Chicago White Sox accused in Black Sox scandal are acquited, however Landis throws them out of baseball |
| August 5 | 1st radio baseball broadcast Pirates-8, Phillies-0 (KDKA, Pitts) |
| August 5 | Treaty of Berlin: U.S. and Germany sign separate peace treaty |
| August 6 | Clason Point, Bronx to College Point, Queens muni ferry system begins |
| August 7 | Cyclist Piet Moeskops becomes world champ sprinter |
| August 10 | Franklin D. Roosevelt stricken with polio at summer home on Canadian Is of Campobello |
| August 13 | Simon Kaufman and Marc Connelly's "Dulcy," premieres in New York City |
| August 19 | Ty Cobb, is 4th to get 3,000 hits |
| August 20 | 35th U.S. Womens Tennis: Molla B Mallory beats M Browne (46 64 62) |
| August 22 | J. Edgar Hoover becomes asst director of FBI |
| August 24 | Battle of Sakaray Valley begins between Turkey and Greece |
| August 24 | British airship R-38 crashes in Humber, 44 die |
| August 25 | U.S. signs peace treaty with Germany |
| August 25 | Yankee pitcher Harry Harper hits 3 batters in an inning tying record |
| August 27 | J E Clair of Acme Packing Co of Green Bay granted an NFL franchise |
| August 28 | 2nd Pan-African Congress meets (London, Brussels and Paris) |
| August 28 | Babe Ruth starts streak of an extra-base hit in 9 straight games |
| September 1 | Nederlander Theater opens at 208 W 41 St. New York City (Billy Rose, Trafalgar) |
| September 3 | 16th Davis Cup: USA beats Japan in New York (5-0) |
| September 3 | KPB, Communist Party of Belgium forms |
| September 5 | Walter Johnson sets strikeout mark at 2,287 |
| September 8 | 1st Miss America crowned (Margaret Gorman of Washington D.C.) |
| September 15 | Pope Benedictus XV publishes encyclical Alcohol Paraclitus |
| September 15 | WBZ-AM in Boston MA begins radio transmissions |
| September 19 | 41st U.S. Mens Tennis: William T Tilden beats Wm M Johnston (61 63 61) |
| September 21 | Gas explodes at Bradishe Aniline chemical works in Germany, 565 die |
| September 21 | Pope Benedictus XV donates 1 million lire to feed Russians |
| September 22 | Estonia and Lithuania admitted to League of Nations |
| September 22 | Music Box Theater opens at 239 W 45th St. New York City |
| September 26 | Yankee Ruth hits home runs 57 and 58 to beat Indians 8-7 |
| September 27 | Yankees beat Indians 21-7 in Polo Grounds |
| September 28 | 4th PGA Championship: Walter Hagen at Inwood CC Far Rockaway NY |
| September 29 | Pirates drop doubleheader to Cards to allow idle Giants to clinch NL |
| October 1 | WJZ, Newark New Jersey begins broadcasting |
| October 2 | New York Yankee Babe Ruth hits then record 59th HR |
| October 4 | League of Nations refuses to assist starving Russians |
| October 5 | 1st World Series radio broadcast, Yankees beat Giants 3-0 |
| October 5 | Present constitution of Liechtenstein comes into effect |
| October 6 | Century Theater opens at 7th Ave and 59th St. New York City (demolished 1962) |
| October 6 | Fewest hits in World Series Game, 5, Yankees (3) beat Giants (2), 3-0 |
| October 9 | Babe Ruth's 1st WS homer; only Sunday game ever pitched by Carl Mays |
| October 10 | NFL Decatur Staleys become Chicago Staleys, win 14-10 |
| October 13 | New York Giants beat New York Yankees, 5 games to 3 in 18th World Series |
| October 16 | Babe Ruth, Bob Meusel, and Bill Piercy defy Landis ban on World Series |
| October 16 | Jim Conzelman takes over as coach of Rock Island Independents from Frank Coughlin-only mid-game coaching change in NFL history |
| October 17 | Belgium's public library law goes into force |
| October 21 | Tuschinski Theater opens in Amsterdam |
| October 23 | Green Bay Packers play 1st NFL game, 7-6 win over Minneapolis |
| October 23 | Leos Janacek's opera "Kat'a Kabanova," premieres in Brno |
| October 26 | Solomon Porter Hood named minister to Liberia |
| October 28 | Amsterdam's Tuschinski movie theater opens |
| October 31 | Federation Sportive Feminine International forms (1st woman track and field association) |
| November 1 | National Birth Control League and Voluntary Parenthood League merge as American Birth Control League |
| November 2 | Eugene O'Neill's "Anna Christie," premieres in New York City |
| November 7 | Ed Wynn's musical "Perfect Fool," premieres in New York City |
| November 9 | Partito Nazionalista Fascista, forms in Italy by Mussolini |
| November 11 | President Harding dedicates Tomb of Unknown Soldier (Arlington Cemetary) |
| November 12 | Washington Conference for Limitation of Armaments |
| November 13 | "Sheik," starring Rudolph Valentino, is released |
| November 13 | U.S., France, Japan and British Empire sign a Pacific Treaty |
| November 15 | KYW-AM in Philadelphia, Pennsylvania begins radio transmissions |
| November 23 | President Harding signs Willis Campell Act (anti-beer bill) forbidding doctors prescribing beer or liquor for medicinal purposes |
| November 28 | Ascension of 'Abdu'l-Baha (Baha'i festival-Qawl 6, 78) |
| November 29 | Coldest day in Nov in Netherlands -14.0 degrees C |
| November 29 | Z Parenteau and Schuyler Green's musical "Kiki," premieres in New York City |
| December 1 | 1st U.S. helium-filled dirigible makes 1st flight |
| December 1 | U.S. Post Office establishes philatelic agency |
| December 3 | 9th CFL Grey Cup: Toronto Argonauts defeats Edmonton Eskimos, 23-0 |
| December 6 | Anglo-Irish Treaty signed; Ireland receives dominion status; partition creates Northern Ireland |
| December 7 | KWG-AM in Stockton California begins radio transmissions |
| December 8 | Eamon de Valera publicly repudiates Anglo-Irish Treaty |
| December 20 | AL votes to return to best-of-7 World Series, while NL votes best-of-9 Judge Kenesaw Mountain Landis casts deciding vote for best-of-7 |
| December 21 | Supreme Court rules labor injunctions and picketing unconstitutional |
| December 29 | William Lyon Mackenzie King succeeded Arthur Meighen as Canadian PM |
| December 31 | Last San Francisco firehorses retired |
