1721 in History
January 25 Czar Peter the Great ends Russian-orthodox patriarchy
March 9 English Chancellor Exchequer John Aislabie confined in London Tower
March 24 Johann Sebastian Bach opens his Brandenburgse Concerts
March 27 France and Spain sign Treaty of Madrid
April 3 Robert Walpole becomes England's 1st Lord of the Treasury
April 26 Smallpox vaccination 1st administrated
May 8 Michelangiolo dei Conti replaces Pope Clement XI, as Innocent XIII
May 25 John Copson becomes America's 1st insurance agent
May 29 South Carolina formally incorporated as a royal colony
June 13 England signs Treaty of Madrid
June 26 Dr. Zabdiel Boylston gives 1st smallpox inoculations in America
August 30 Russian/Swedish Peace of Nystad, ends North Sea War
October 22 Czar Peter the Great becomes "All-Russian Imperator"
November 1 Prince Eugenius of Savoye unveals statue of himself